Thesis project :
Do interactions with the host’s microbiota influence pathogens evolution ?
- Jean-baptiste Ferdy (EDB, UPS, Toulouse)
- Sophie Gaudriault (DGIMI, UM, Montpellier)
Main questions :
Which microorganisms of the host’s microbiota (e.g. the comensal intestinal flora) are potential competitors of the pathogen during the infection ?
What impact do these competitors have on the pathogen and its vector life cycle ?
Model species :
Xenorhabdus nematophila is an insect pathogen transmitted by a soil nematode vector Steinernema carpocapsae.